⚠️ Information is for educational purposes and complements, but does not replace, medical treatment.

What is the yellow stuff in a healing wound?

How to Remove Yellow Slough From a Wound: Debridement Methods

How to get rid of yellow slough in a wound?

The Quick Answer

**Never attempt self-removal**—slough requires professional debridement. Methods include: **autolytic** (moisture-donating dressings), **enzymatic** (collagenase ointment), **mechanical** (irrigation), **larval therapy** (sterile maggots), or **surgical** (scalpel/scissors excision). Selection depends on wound characteristics, patient factors, and slough adherence—always under clinical supervision.

Why We Ask This

Well-intentioned patients often attempt dangerous self-removal using tweezers or harsh scrubbing, causing trauma that reopens healing tissue and introduces bacteria—significantly worsening outcomes especially in diabetic or vascular-compromised individuals.

The Practical Science

Debridement resets the wound healing cascade by eliminating biofilm habitats and exposing viable tissue to growth factors. Evidence shows wounds with >25% slough coverage heal 3× slower without intervention due to sustained protease activity degrading healing proteins.

In Clinical Practice

For dry, adherent slough on a heel ulcer, a clinician might apply hydrogel dressing overnight to rehydrate tissue, then gently irrigate with saline the next day to lift loosened debris—demonstrating staged removal that minimizes trauma while advancing healing.

References & Context

Think You Know Slough Wounds? - Net Health
"Sterile fly larvae are strategically placed in a wound to selectively remove necrotic tissue and aid healing. Surgical debridement. Involves excising necrotic tissue using a scalpel, curette, or scissors. It's appropriate for both slough and eschar removal.Nov 10, 2025"