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yellow slough in wound bed

What Does Yellow Slough Mean in a Wound? Clinical Interpretation Guide

What does yellow slough mean in a wound?

The Quick Answer

**Yellow slough** indicates non-viable, necrotic tissue composed of dead white blood cells, fibrin, and cellular debris accumulating in the wound bed. It signals stalled healing—typically during prolonged inflammation—and creates a breeding ground for bacteria. Unlike healthy granulation tissue, slough impedes epithelialization and requires clinical intervention for proper wound progression.

Why We Ask This

Patients often mistake yellow slough for normal healing discharge or infection pus, causing anxiety about whether their wound is worsening or if they've caused harm through improper care. This confusion delays appropriate treatment seeking.

The Practical Science

Slough forms when the inflammatory phase extends beyond 4–6 days due to poor perfusion, infection, or biofilm presence. Histologically, it consists of denatured proteins and leukocyte remnants that physically block fibroblast migration and angiogenesis essential for tissue repair.

In Clinical Practice

During wound assessment, a clinician would gently probe the yellow tissue with a cotton swab—if it doesn't bleed and feels stringy or adherent, it's confirmed slough requiring debridement rather than simple cleansing.

References & Context

Slough and Eschar: Wound Care SHORT | ‪@LevelUpRN‬ - YouTube
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